Background and Objectives: Helicobacter pylori is a spiral shaped, Gram-negative rod with 5-7 flagella at one end and have been considered as a primary risk factor for peptic ulcer disease and gastric cancer. This study aimed to the prevalence and detection of H.pyori among Rizary Teaching Hospital/ Erbil City. Objective: Study the prevalence and detection of H. pyori among Rizary Teaching Hospital. Methods: Seven hundred and twenty- six (726) human stool samples were collected from Rizgary Teaching Hospital /Erbil City from October 2018 to February 2019. The samples were collected and the test performed in the microbiology laboratory Collage of Health Sciences by using antigen stool detection tests. Results: The study showed that among 726 samples in Rizgary Teaching Hospital H. pylori positive results showed in 380(52%) and H. pylori infection in female was higher than male, the infection was higher among (16-45) years than patients aged between (15- 16 and 55-65) years, when we studied H. pylori infection according to months it was showed that the prevalence of H. pylori infection appeared in all studied months the higher infection showed during October 94 and November 84 and there was a significant difference between the samples related to months. Conclusion: Among 726 samples H. pylori was positive in 380(52%), H. pylori infection in female was higher than male. The infection was higher among (16-45) years than patients aged among (55-65) years.