Background: Migraine is frequently associated with psychiatric disorders and comorbidity with psychiatric disorders raises the global burden of migraine. Objectives: To detect psychiatric comorbidity in patients suffering from migraine. Patients and Methods: A descriptive study involving 192 patients with migraine who fulfilled the International Classification of Headache Disorders-2 2004 (ICHD-2). Diagnostic and Statistical Manual of mental disorders, 4th Text Revised (DSM-IVTR) was used to classify the psychiatric disorders, among them. All patients were interviewed by means of the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) for identification of the content of obsessive compulsive symptoms. Results: The majority of the migraineurs were with throbbing unilateral headache (79.1%), (31.3%) of the patients were with one per month in frequency of attack and (41.7%) of them had family history of migraine. The provoking factors of the attack were reported in (37.5%) of the migrainerurs.(75%) of the patients had psychiatric disorders. The commonest psychiatric disorders were generalized anxiety disorder (31.25%) followed by depressive disorder (19.8%). 
Conclusion :(75%) of patients with migraine of the present study had psychiatric disorders.