Kirkuk Journal of Medical Sciences

Triglyceride and High density lipoprotein Cholesterol ratio in Patients with Acute Coronary Syndrome

Document Type : Original research

Authors

Sherzad Saber Jawameer 1
Basil Najeeb Saeed 2

1 MBChB, FIBMS, Internal Medicine Specialist, Azadi Teaching Hospital, Kirkuk, Iraq.

2 FRCP ,MRCP ,MD ,DCC, Professor in internal medicine / cardiology, Department of Internal Medicine/Baghdad Teaching Hospital, College of Medicine, Baghdad University, Baghdad, Iraq

https://doi.org/10.32894/kjms.2021.170174
Abstract
Background: Ischemic heart disease is the leading cause of death worldwide. This study assessed the prevalence of elevated triglyceride-to-HDL cholesterol ratio among acute coronary syndrome patients versus a control group, highlighting its role in atherogenesis.
Methods: A case-control study included 100 ACS inpatients and 100 non-ACS outpatients at Baghdad Teaching Hospital from July to November 2013. Demographic and clinical data were collected, and lipid profiles analyzed.
Result: The TG/HDL-C ratio (≥5) was higher in 58% of ACS patients versus 10% of controls. ACS patients had significantly lower HDL-C and higher TG levels. Triglycerides varied by ACS type, being lowest in unstable angina and highest in STEMI and NSTEMI (P=0.031).
Conclusions: High TG, low HDL-C, and elevated TG/HDL-C ratio are strongly associated with ACS, indicating their value as risk markers for early detection and prevention.

Keywords

Acute coronary syndrome
Hypertriglyceridemia
Atherosclerosis
Subjects