Document Type : Original research
Authors
1 Kirkuk Teaching Hospital, Department of Medicine, Kirkuk Health Directorate, Kirkuk, IRAQ.
2 Department of Neurology, Al-Yarmouk Teaching Hospital, Baghdad, IRAQ.
Abstract
Background: Status epilepticus (SE) is a serious complication of cerebral venous thrombosis (CVT). However, the risk factors associated with the development of SE and its impact on outcomes remain a subject of ongoing debate. This study aimed to identify predictors of SE in patients with CVT and to assess the relative risk of SE in contributing to mortality and disability compared with CVT patients without SE.
Methods: This was a comparative case series study involving 29 patients with CVT admitted to Al-Yarmouk Teaching Hospital between January 2019 and March 2021. Patients were followed up and re-evaluated at 3 and 6 months post-discharge. Outcomes were assessed using the modified Rankin Scale (mRS).
Result: Of the 29 CVT patients, 11 (37.9%) developed SE. Significant predictors of SE included decreased level of consciousness (GCS ≤8; p = 0.0001), motor weakness (p = 0.003), and the presence of supratentorial lesions on brain MRI, particularly hemorrhagic lesions (p = 0.003). At 3 months post-discharge, disability was significantly higher in the SE group (p = 0.006); however, by 6 months, both groups showed comparable recovery (p = 0.345).
Conclusions: Decreased consciousness, motor weakness, and supratentorial hemorrhagic lesions on MRI are significant predictors of SE in CVT patients. SE is associated with increased disability at 3 months, but long-term outcomes at 6 months are favorable in both SE and non-SE groups.
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