Background: Some periodontal bacteria on tooth plaque were shown to be sensitive to extracts from Syzigium aromaticum and Salvadora persica. The study aimed to assess the antimicrobial effect of Syzigium aromaticum and Salvadora persica extracts against dental plaque pathogens.
Methods: Oral swabs were collected from 35 patients with dental plaque, and isolated microorganisms were identified using standard bacteriological methods. Syzigium aromaticum and Salvadora persica extracts were tested against dental plaque microorganisms on Muller Hinton agar at 50% concentration using the paper disks-diffusion technique to measure antimicrobial activity and inhibition zones.
Result: From 35 dental plaque samples, 46 microorganisms were isolated, including Staphylococcus aureus (18), Staphylococcus epidermidis (3), Streptococcus mutans (6), Streptococcus viridans (12), and single isolates of Pseudomonas aeruginosa, Proteus spp., Bacillus spp. Two isolates each of Actinobacillus actinomycetemcomitans and Candida albicans were found. The study revealed that Syzigium aromaticum and Salvadora persica extracts possess antibacterial and antifungal properties against both gram-positive and gram-negative bacteria, as well as fungi.
Conclusions: Syzigium aromaticum and Salvadora persica extracts demonstrated strong antimicrobial efficacy, suggesting their potential for oral hygiene treatment and prevention.