The Relation between Chronic Viral Hepatitis B Infection and Helicobacter Pylori Infection

Jafar, Saman Khazal; Abdulkareem, Makwan; Mohammed, Mohammed Omer

doi:10.32894/kjms.2022.136753.1045

The Relation between Chronic Viral Hepatitis B Infection and Helicobacter Pylori Infection

Document Type : Original research

Authors

Saman Khazal Jafar ¹

Makwan Abdulkareem ²

Mohammed Omer Mohammed ³

¹ Internal Medicine Registrar, Internal Medicine Teaching Hospital, Sulaimani Directorate of Health, Sulaimani - Kurdistan Region, Iraq

² Psychiatrist and Mental Health Specialist, Hospital of Treatment Victims of Chemical Weapons, Halabja Directorate of Health, Halabja - Kurdistan Region, Iraq.

³ Professor of Gastroenterology, School of Medicine, Faculty of Medical Sciences, University of Sulaimani, Downtown Campus, Sulaimani - Kurdistan Region, Iraq

https://doi.org/10.32894/kjms.2022.136753.1045

Abstract

Background: The relation between H. pylori infection and Viral Hepatitis has been subjected to substantial research in recent years, however, this relationship has not been comprehensively studied in Al Sulaymaniyah. The objective of this study is to Investigate the association between HBV infection and the H. pylori infection.
Method and patient: A case-control study using data from 130 participants, from January 2020 to March 2021. Data is divided into two groups, a study group which consists of 65 persons of confirmed hepatitis B infection via PCR, and a control group of 65 persons with confirmed Hepatitis B negative by Hepatitis B surface antigen test, we used stool antigen test to confirm the presence or absence of H. Pylori infection in both groups.
Result: 32% of the study group is infected with H. pylori and 15% in the control group have been tested positive for H. pylori infection. The regression analysis results reveal strong evidence that HBV infection increases the likelihood of H. pylori infection. This relationship is very robust and consistent even after controlling a vast number of variables as confounding and medical factors.
Conclusions: Patients with HBV infection are more vulnerable to H. pylori infection.

Keywords

H. pylori infection

HBV infection

case-control study

Subjects